I know a consistant intake of about 500mg a day (built up slowly over many years :P) seems to be perfectly fine, only very rarely d I have any ill effects (and I usually go significantly over in such a case) where my hands shake slightly for a couple of hours and my body feels somewhat lighter than it ought.
I do have one more warning. Following an accidental overdose (about 3grams was mine, didn't read the pills before I took them, don't do that :P) even very minor amounts of caffeine can apparently have acute effects. I went to work after 48 hours of being wake and having taken the pills about 30 minutes prior and about an hour into work I had what I thought was just one of my regular panic attacks (job was very physically intensive, in 85+ degree heat at all times, and very stressful, I was used to them) only I ended up collapsing -- for the next month or so even one cup of soda would cause extreme jitters.
So yeah, word to the foolish -- if you accidentally overdose, you may not want to use caffeine for a while afterwards.
Oh and also, I agree with the general consensus that its generally best to avoid caffeine pills, more than one or two -servings- of an energy drink on occasion, ungodly amounts of coffee, and all that stuff :P Because it really is very uncomfortable.
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